Conformations of linear DNA
نویسندگان
چکیده
منابع مشابه
Conformations of Linear DNA
We examine the conformations of a model for underand overwound DNA. The molecule is represented as a cylindrically symmetric elastic string subjected to a stretching force and to constraints corresponding to a specification of the link number. We derive a fundamental relation between the Euler angles that describe the curve and the topological linking number. Analytical expressions for the spat...
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Studies of circular DNA confined to nanofluidic channels are relevant both from a fundamental polymer-physics perspective and due to the importance of circular DNA molecules in vivo. We here observe the unfolding of DNA from the circular to linear configuration as a light-induced double strand break occurs, characterize the dynamics, and compare the equilibrium conformational statistics of line...
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We examine the conformations of a model for short closed DNA. The molecule is represented as a cylindrically symmetric elastic string with a constraint corresponding to a specification of the linking number. We obtain analytic expressions for configuration, elastic energy, twist and linking number for a family of solutions spanning from a circle to a ’figure eight’. We suggest ways to use our c...
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We examine the conformations of a model for a short segment of closed DNA. The molecule is represented as a cylindrically symmetric elastic rod with a constraint corresponding to a specification of the linking number. We obtain analytic expressions leading to the spatial configuration of a family of solutions representing distortions that interpolate between the circular form of DNA and a figur...
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Molecular modelling has been used to probe the conformational preferences of double stranded DNA-RNA hybrids. As might be expected, the sugars of the DNA strand have higher conformational flexibility, but, for the majority of the repetitive sequences studied, these sugars prefer a C2-endo pucker, while ribose sugars uniformly adopt a C3-endo pucker. This gives rise to a strongly heteronomous du...
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ژورنال
عنوان ژورنال: Physical Review E
سال: 1997
ISSN: 1063-651X,1095-3787
DOI: 10.1103/physreve.55.7364